Pizotifen Relieves Acute Migraine Symptoms
نویسنده
چکیده
To The Editor: Various pharmacological agents are used for the treatment of migraine. In the last five years, various drug companies in Bangladesh have been marketing pizotifen as a preventive treatment of all types of migraine. Pizotifen is a serotonin antagonist acting mainly at the 5HT1, 5-HT2A and 5HT2C receptors. It also has some activity as an antihistamine (1). Pizotifen is a wellestablished preventative therapy of migraine. I would like to report my own experience in using pizotifen in treating the acute attacks of migraine.
منابع مشابه
Calcium channel antagonism by pizotifen.
Pizotifen is a clinically effective anti-migraine agent with potent anti-serotonin and anti-histamine properties. Pizotifen is equipotent in blocking contractions of the canine basilar artery induced by serotonin, norepinephrine or calcium chloride. As a result, the primary action of pizotifen in the canine basilar artery system appears to be calcium channel blockade and not selective antagonis...
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